产品货号:
Z28181
中文名称:
TGFBR1抗体
英文名称:
Anti-TGFBR1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TGFBR1 Antibody |
指标别名 | transforming growth factor beta receptor 1;AAT5;ACVRLK4;ALK-5;ALK5;ESS1;LDS1;LDS1A;LDS2A;MSSE;SKR4;TBR-i;TBRI;TGFR-1;tbetaR-I;TGFBR1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | TGFBR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR1 (149-186aa HNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTT),identical to the related mouse and rat sequences. |
实际分子量 | 56KD |
成分 | 500μg/mL antibody with PBS,1mg BSA |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Transforming growth factor,beta receptor I is a TGF beta receptor.TGFBR1 is its human gene.The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta,transducing the TGF-beta signal from the cell surface to the cytoplasm.Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).TGFB1 regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFBR2 and activation of TGFBR1.Both are transmembrane serine/threonine receptor kinases.The TGFBR1 receptor may be inactivated in many of the cases of human tumor cells refractory to TGFB-mediated cell cycle arrest. |
Uniprot ID | P36897 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | TGFBR1 |
蛋白名全称 | TGF-beta receptor type-1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
相关搜索:TGFBR1抗体,TGFBR1多抗,Anti-TGFBR1 Antibody